Facility Publications

This is a list of publications in which flow cytometry data was acquired in our facility. We kindly ask investigators to acknowledge the IGC Flow Cytometry Facility in the publications in which our services were provided.



Duarte, Nádia; Coelho, Inês; Holovanchuk, Denys; Inês Almeida, Joana; Penha-Gonçalves, Carlos and Paula Macedo, Maria. Dipeptidyl Peptidase-4 Is a Pro-Recovery Mediator During Acute Hepatotoxic Damage and Mirrors Severe Shifts in Kupffer Cells. Hepatology Communications. 2018;2(9):1080–1094. [doi]

Seixas, Elsa; Escrevente, Cristina; Seabra, Miguel C. and Barral, Duarte C.. Rab GTPase regulation of bacteria and protozoa phagocytosis occurs through the modulation of phagocytic receptor surface expression. Scientific Reports. 2018;8(1):12998. [doi]

Rodrigues-Duarte, Lurdes; Pandya, Yash and Neres, Rita. Fetal and maternal innate immunity receptors have opposing effects in severity of experimental malaria in pregnancy: Beneficial roles for fetal-derived TLR4 and IFNAR1. Infection and Immunity. 2018;86(5):IAI.00708–17. [doi]

Passagem-Santos, Diogo; Zacarias, Simone and Perfeito, Lilia. Power law fitness landscapes and their ability to predict fitness. Heredity. 2018;121(5):482–498. [doi]

Lopes, Carla A.M.; Mesquita, Marta; Cunha, Ana Isabel; Cardoso, Joana; Carapeta, Sara; Laranjeira, Cátia; Pinto, António E.; Pereira-Leal, José B.; Dias-Pereira, António; Bettencourt-Dias, Mónica and Chaves, Paula. Centrosome amplification arises before neoplasia and increases upon p53 loss in tumorigenesis. Journal of Cell Biology. 2018;217(7):2353–2363. [doi]


Valente, Rita S.; Nadal-Jimenez, Pol; Carvalho, André F.P.; Vieira, Filipe J.D. and Xavier, Karina B.. Signal integration in quorum sensing enables cross-species induction of virulence in Pectobacterium wasabiae. mBio. 2017;8(3):1–16. [doi]

Tavares, Sandra; Vieira, André Filipe; Taubenberger, Anna Verena; Araújo, Margarida; Martins, Nuno Pimpao; Brás-Pereira, Catarina; Polónia, António; Herbig, Maik; Barreto, Clara; Otto, Oliver; Cardoso, Joana; Pereira-Leal, José B.; Guck, Jochen; Paredes, Joana and Janody, Florence. Actin stress fiber organization promotes cell stiffening and proliferation of pre-invasive breast cancer cells. Nature Communications. 2017;8(May). [doi]

Tavares, Barbara; Jacinto, Raquel; Sampaio, Pedro; Pestana, Sara; Pinto, Andreia; Vaz, Andreia; Roxo-Rosa, Mónica; Gardner, Rui; Lopes, Telma; Schilling, Britta; Henry, Ian; Saúde, Leonor and Lopes, Susana Santos. Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of Foxj1a in zebrafish left-right organizer. eLife. 2017;6:1–26. [doi]

Sousa, Ana; Ramiro, Ricardo S.; Barroso-Batista, João; Güleresi, Daniela; Louren\vco, Marta and Gordo, Isabel. Recurrent reverse evolution maintains polymorphism after strong bottlenecks in commensal gut bacteria. Molecular Biology and Evolution. 2017;34(11):2879–2892. [doi]

Schmidt, Anja. Plant Germline Development. 2017;1669. [doi]

Ramos-Nascimento, Ana; Kellen, Bárbara; Ferreira, Filipe; Alenquer, Marta; Vale-Costa, Sílvia; Raposo, Graça and Delevoye, Cédric. KIF13A mediates trafficking of influenza A virus ribonucleoproteins. Journal of Cell Science. 2017;130(23):4038–4050. [doi]

Pirzgalska, Roksana M.; Seixas, Elsa; Seidman, Jason S.; Link, Verena M.; Sánchez, Noelia Martínez; Mahú, Inês; Mendes, Raquel; Gres, Vitka; Kubasova, Nadiya; Morris, Imogen; Arús, Bernardo A.; Larabee, Chelsea M.; Vasques, Miguel; Tortosa, Francisco; Sousa, Ana L.; Anandan, Sathyavathy; Tranfield, Erin; Hahn, Maureen K.; Iannacone, Matteo; Spann, Nathanael J.; Glass, Christopher K. and Domingos, Ana I.. Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine. Nature Medicine. 2017;23(11):1309–1318. [doi]

Pereira, Mafalda M.A.; Mahú, Inês; Seixas, Elsa; Martinéz-Sánchez, Noelia; Kubasova, Nadiya; Pirzgalska, Roksana M.; Cohen, Paul; Dietrich, Marcelo O.; López, Miguel; Bernardes, Gonçalo J.L. and Domingos, Ana I.. Corrigendum: A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages. Nature communications. 2017;8:15673. [doi]

Moura de Sousa, Jorge and Balbontín Roberto; Durão, Paulo and Gordo, Isabel. Multidrug-resistant bacteria compensate for the epistasis between resistances. PLoS Biology. 2017;15(4). [doi]

Gualda, Emilio J.; Pereira, Hugo; Martins, Gabriel G.; Gardner, Rui and Moreno, Nuno. Three-dimensional imaging flow cytometry through light-sheet fluorescence microscopy. Cytometry Part A. 2017;91(2):144–151. [doi]

Gouveia, Zélia; Carlos, Ana R.; Yuan, Xiaojing; Aires-da-Silva, Frederico; Stocker, Roland; Maghzal, Ghassan J.; Leal, Sónia S.; Gomes, Cláudio M.; Todorovic, Smilja; Iranzo, Olga; Ramos, Susana; Santos, Ana C.; Hamza, Iqbal; Gonçalves, João and Soares, Miguel P.. Characterization of plasma labile heme in hemolytic conditions. FEBS Journal. 2017;284(19):3278–3301. [doi]

Gonçalves, Lígia Antunes; Rodo, Joana; Rodrigues-Duarte, Lurdes and de Moraes, Luciana Vieira. HGF secreted by activated kupffer cells induces apoptosis of Plasmodium-infected hepatocytes. Frontiers in Immunology. 2017;8(FEB):1–11. [doi]

Costa, N.; Marques, O.; Godinho, S. I.; Carvalho, C.; Leal, B.; Figueiredo, A. M.; Vasconcelos, C.; Marinho, A.; Moraes-Fontes, M. F.; Gomes da Costa, A.; Ponte, C.; Campanilho-Marques, R.; Cóias, T.; Martins, A. R.; Viana, J. F.; Lima, M.; Martins, B. and Fesel, C.. Two separate effects contribute to regulatory T cell defect in systemic lupus erythematosus patients and their unaffected relatives. Clinical and Experimental Immunology. 2017;189(3):318–330. [doi]

Bonnet, Marie; Sarmento, Leonor Morais; Martins, Ana C.; Sobral, Daniel; Silva, Joana and Demengeot, Jocelyne. iRAGu: A novel inducible and reversible mouse model for ubiquitous recombinase activity. Frontiers in Immunology. 2017;8(NOV):1–13. [doi]


Cardoso, M Margarida; Peça, Inês N; Raposo, Cláudia D; Petrova, Krasimira T; Barros, M Teresa; Gardner, Rui and Bicho, A. Doxorubicin-loaded galactose-conjugated poly(d,l-lactide-co-glycolide) nanoparticles as hepatocyte-targeting drug carrier. Journal of Microencapsulation. 2016;33(4):315–322. [doi]

Carqueijeiro, Ines Teto; Guimarães, Ana Luísa; Bettencourt, Sara; Martínez-Cortés, Teresa; Guedes, Joana; Gardner, Rui; Lopes, Telma; Andrade, Cláudia; Bispo, Cláudia; Martins, Nuno Pimpão; Andrade, Paula; Valentão, Patrícia; Valente, Inês Maria; Rodrigues, José António; Duarte, Patrícia and Sottomayor, Mariana. Isolation of cells specialized in anticancer alkaloid metabolism by fluorescence activated cell sorting. Plant Physiology. 2016:pp.00588.2016. [doi]

Calisto, Filipa; Refojo, Patrícia N.; Bispo, Cláudia; Andrade, Cláudia; Gardner, Rui; Madl, Tobias; López de Lacey, Antonio; Teixeira, Miguel and Pereira, Manuela M.. Characterization and activity of Alternative Complex III from Rhodothermus marinus. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 2016;1857(Supplement):e36. [doi]

Barsky, Lora W.; Black, Michele; Cochran, Matthew; Daniel, Benjamin J.; Davies, Derek; DeLay, Monica; Gardner, Rui; Gregory, Michael; Kunkel, Desiree; Lannigan, Joanne; Marvin, James; Salomon, Robert; Torres, Carina and Walker, Rachael. International Society for Advancement of Cytometry (ISAC) flow cytometry shared resource laboratory (SRL) best practices. Cytometry Part A. 2016:1–14. [doi]


Traunecker, Emmanuel; Gardner, Rui; Fonseca, Jo??o Eurico; Polido-Pereira, Joaquim; Seitz, Michael; Villiger, Peter M.; Iezzi, Giandomenica and Padovan, Elisabetta. Blocking of LFA-1 enhances expansion of Th17 cells induced by human CD14+CD16++ nonclassical monocytes. European Journal of Immunology. 2015;45(5):1414–1425. [doi]

Riddell, Andrew; Gardner, Rui; Perez-Gonzalez, Alexis; Lopes, Telma and Martinez, Lola. Rmax: A systematic approach to evaluate instrument sort performance using center stream catch. Methods. Elsevier Inc.; 2015;82:64–73. [doi]

Rebelo, Maria; Tempera, Carolina; Bispo, Claudia; Andrade, Claudia; Gardner, Rui; Shapiro, Howard M. and H??nscheid, Thomas. Light depolarization measurements in malaria: A new job for an old friend. Cytometry Part A. 2015;87(5):437–445. [doi]

Peça, Inês N.; Bicho, A.; Gardner, Rui and Cardoso, M. Margarida. Control of doxorubicin release from magnetic Poly(dl-lactide-co-glycolide) nanoparticles by application of a non-permanent magnetic field. Journal of Nanoparticle Research. 2015;17(11):427. [doi]

Kappel, Christian; Trost, Gerda; Czesnick, Hjördis; Ramming, Anna; Kolbe, Benjamin; Vi, Son Lang; Bispo, Cláudia; Becker, Jörg D.; de Moor, Cornelia and Lenhard, Michael. Genome-Wide Analysis of PAPS1-Dependent Polyadenylation Identifies Novel Roles for Functionally Specialized Poly(A) Polymerases in Arabidopsis thaliana. PLoS Genetics. 2015;11(8):1–30. [doi]