Facility Publications



Duarte, Nádia; Coelho, Inês; Holovanchuk, Denys; Inês Almeida, Joana; Penha-Gonçalves, Carlos and Paula Macedo, Maria. Dipeptidyl Peptidase-4 Is a Pro-Recovery Mediator During Acute Hepatotoxic Damage and Mirrors Severe Shifts in Kupffer Cells. Hepatology Communications. 2018;2(9):1080–1094. [doi]

Seixas, Elsa; Escrevente, Cristina; Seabra, Miguel C. and Barral, Duarte C.. Rab GTPase regulation of bacteria and protozoa phagocytosis occurs through the modulation of phagocytic receptor surface expression. Scientific Reports. 2018;8(1):12998. [doi]

Rodrigues-Duarte, Lurdes; Pandya, Yash and Neres, Rita. Fetal and maternal innate immunity receptors have opposing effects in severity of experimental malaria in pregnancy: Beneficial roles for fetal-derived TLR4 and IFNAR1. Infection and Immunity. 2018;86(5):IAI.00708–17. [doi]

Passagem-Santos, Diogo; Zacarias, Simone and Perfeito, Lilia. Power law fitness landscapes and their ability to predict fitness. Heredity. 2018;121(5):482–498. [doi]

Lopes, Carla A.M.; Mesquita, Marta; Cunha, Ana Isabel; Cardoso, Joana; Carapeta, Sara; Laranjeira, Cátia; Pinto, António E.; Pereira-Leal, José B.; Dias-Pereira, António; Bettencourt-Dias, Mónica and Chaves, Paula. Centrosome amplification arises before neoplasia and increases upon p53 loss in tumorigenesis. Journal of Cell Biology. 2018;217(7):2353–2363. [doi]


Valente, Rita S.; Nadal-Jimenez, Pol; Carvalho, André F.P.; Vieira, Filipe J.D. and Xavier, Karina B.. Signal integration in quorum sensing enables cross-species induction of virulence in Pectobacterium wasabiae. mBio. 2017;8(3):1–16. [doi]

Tavares, Sandra; Vieira, André Filipe; Taubenberger, Anna Verena; Araújo, Margarida; Martins, Nuno Pimpao; Brás-Pereira, Catarina; Polónia, António; Herbig, Maik; Barreto, Clara; Otto, Oliver; Cardoso, Joana; Pereira-Leal, José B.; Guck, Jochen; Paredes, Joana and Janody, Florence. Actin stress fiber organization promotes cell stiffening and proliferation of pre-invasive breast cancer cells. Nature Communications. 2017;8(May). [doi]

Tavares, Barbara; Jacinto, Raquel; Sampaio, Pedro; Pestana, Sara; Pinto, Andreia; Vaz, Andreia; Roxo-Rosa, Mónica; Gardner, Rui; Lopes, Telma; Schilling, Britta; Henry, Ian; Saúde, Leonor and Lopes, Susana Santos. Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of Foxj1a in zebrafish left-right organizer. eLife. 2017;6:1–26. [doi]

Sousa, Ana; Ramiro, Ricardo S.; Barroso-Batista, João; Güleresi, Daniela; Louren\vco, Marta and Gordo, Isabel. Recurrent reverse evolution maintains polymorphism after strong bottlenecks in commensal gut bacteria. Molecular Biology and Evolution. 2017;34(11):2879–2892. [doi]

Schmidt, Anja. Plant Germline Development. 2017;1669. [doi]

Ramos-Nascimento, Ana; Kellen, Bárbara; Ferreira, Filipe; Alenquer, Marta; Vale-Costa, Sílvia; Raposo, Graça and Delevoye, Cédric. KIF13A mediates trafficking of influenza A virus ribonucleoproteins. Journal of Cell Science. 2017;130(23):4038–4050. [doi]

Pirzgalska, Roksana M.; Seixas, Elsa; Seidman, Jason S.; Link, Verena M.; Sánchez, Noelia Martínez; Mahú, Inês; Mendes, Raquel; Gres, Vitka; Kubasova, Nadiya; Morris, Imogen; Arús, Bernardo A.; Larabee, Chelsea M.; Vasques, Miguel; Tortosa, Francisco; Sousa, Ana L.; Anandan, Sathyavathy; Tranfield, Erin; Hahn, Maureen K.; Iannacone, Matteo; Spann, Nathanael J.; Glass, Christopher K. and Domingos, Ana I.. Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine. Nature Medicine. 2017;23(11):1309–1318. [doi]

Pereira, Mafalda M.A.; Mahú, Inês; Seixas, Elsa; Martinéz-Sánchez, Noelia; Kubasova, Nadiya; Pirzgalska, Roksana M.; Cohen, Paul; Dietrich, Marcelo O.; López, Miguel; Bernardes, Gonçalo J.L. and Domingos, Ana I.. Corrigendum: A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages. Nature communications. 2017;8:15673. [doi]

Moura de Sousa, Jorge and Balbontín Roberto; Durão, Paulo and Gordo, Isabel. Multidrug-resistant bacteria compensate for the epistasis between resistances. PLoS Biology. 2017;15(4). [doi]

Gualda, Emilio J.; Pereira, Hugo; Martins, Gabriel G.; Gardner, Rui and Moreno, Nuno. Three-dimensional imaging flow cytometry through light-sheet fluorescence microscopy. Cytometry Part A. 2017;91(2):144–151. [doi]

Gouveia, Zélia; Carlos, Ana R.; Yuan, Xiaojing; Aires-da-Silva, Frederico; Stocker, Roland; Maghzal, Ghassan J.; Leal, Sónia S.; Gomes, Cláudio M.; Todorovic, Smilja; Iranzo, Olga; Ramos, Susana; Santos, Ana C.; Hamza, Iqbal; Gonçalves, João and Soares, Miguel P.. Characterization of plasma labile heme in hemolytic conditions. FEBS Journal. 2017;284(19):3278–3301. [doi]

Gonçalves, Lígia Antunes; Rodo, Joana; Rodrigues-Duarte, Lurdes and de Moraes, Luciana Vieira. HGF secreted by activated kupffer cells induces apoptosis of Plasmodium-infected hepatocytes. Frontiers in Immunology. 2017;8(FEB):1–11. [doi]

Costa, N.; Marques, O.; Godinho, S. I.; Carvalho, C.; Leal, B.; Figueiredo, A. M.; Vasconcelos, C.; Marinho, A.; Moraes-Fontes, M. F.; Gomes da Costa, A.; Ponte, C.; Campanilho-Marques, R.; Cóias, T.; Martins, A. R.; Viana, J. F.; Lima, M.; Martins, B. and Fesel, C.. Two separate effects contribute to regulatory T cell defect in systemic lupus erythematosus patients and their unaffected relatives. Clinical and Experimental Immunology. 2017;189(3):318–330. [doi]

Bonnet, Marie; Sarmento, Leonor Morais; Martins, Ana C.; Sobral, Daniel; Silva, Joana and Demengeot, Jocelyne. iRAGu: A novel inducible and reversible mouse model for ubiquitous recombinase activity. Frontiers in Immunology. 2017;8(NOV):1–13. [doi]


Cardoso, M Margarida; Peça, Inês N; Raposo, Cláudia D; Petrova, Krasimira T; Barros, M Teresa; Gardner, Rui and Bicho, A. Doxorubicin-loaded galactose-conjugated poly(d,l-lactide-co-glycolide) nanoparticles as hepatocyte-targeting drug carrier. Journal of Microencapsulation. 2016;33(4):315–322. [doi]

Carqueijeiro, Ines Teto; Guimarães, Ana Luísa; Bettencourt, Sara; Martínez-Cortés, Teresa; Guedes, Joana; Gardner, Rui; Lopes, Telma; Andrade, Cláudia; Bispo, Cláudia; Martins, Nuno Pimpão; Andrade, Paula; Valentão, Patrícia; Valente, Inês Maria; Rodrigues, José António; Duarte, Patrícia and Sottomayor, Mariana. Isolation of cells specialized in anticancer alkaloid metabolism by fluorescence activated cell sorting. Plant Physiology. 2016:pp.00588.2016. [doi]

Calisto, Filipa; Refojo, Patrícia N.; Bispo, Cláudia; Andrade, Cláudia; Gardner, Rui; Madl, Tobias; López de Lacey, Antonio; Teixeira, Miguel and Pereira, Manuela M.. Characterization and activity of Alternative Complex III from Rhodothermus marinus. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 2016;1857(Supplement):e36. [doi]

Barsky, Lora W.; Black, Michele; Cochran, Matthew; Daniel, Benjamin J.; Davies, Derek; DeLay, Monica; Gardner, Rui; Gregory, Michael; Kunkel, Desiree; Lannigan, Joanne; Marvin, James; Salomon, Robert; Torres, Carina and Walker, Rachael. International Society for Advancement of Cytometry (ISAC) flow cytometry shared resource laboratory (SRL) best practices. Cytometry Part A. 2016:1–14. [doi]


Traunecker, Emmanuel; Gardner, Rui; Fonseca, Jo??o Eurico; Polido-Pereira, Joaquim; Seitz, Michael; Villiger, Peter M.; Iezzi, Giandomenica and Padovan, Elisabetta. Blocking of LFA-1 enhances expansion of Th17 cells induced by human CD14+CD16++ nonclassical monocytes. European Journal of Immunology. 2015;45(5):1414–1425. [doi]

Riddell, Andrew; Gardner, Rui; Perez-Gonzalez, Alexis; Lopes, Telma and Martinez, Lola. Rmax: A systematic approach to evaluate instrument sort performance using center stream catch. Methods. Elsevier Inc.; 2015;82:64–73. [doi]

Rebelo, Maria; Tempera, Carolina; Bispo, Claudia; Andrade, Claudia; Gardner, Rui; Shapiro, Howard M. and H??nscheid, Thomas. Light depolarization measurements in malaria: A new job for an old friend. Cytometry Part A. 2015;87(5):437–445. [doi]

Peça, Inês N.; Bicho, A.; Gardner, Rui and Cardoso, M. Margarida. Control of doxorubicin release from magnetic Poly(dl-lactide-co-glycolide) nanoparticles by application of a non-permanent magnetic field. Journal of Nanoparticle Research. 2015;17(11):427. [doi]

Kappel, Christian; Trost, Gerda; Czesnick, Hjördis; Ramming, Anna; Kolbe, Benjamin; Vi, Son Lang; Bispo, Cláudia; Becker, Jörg D.; de Moor, Cornelia and Lenhard, Michael. Genome-Wide Analysis of PAPS1-Dependent Polyadenylation Identifies Novel Roles for Functionally Specialized Poly(A) Polymerases in Arabidopsis thaliana. PLoS Genetics. 2015;11(8):1–30. [doi]